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1

A multiple-dose, safety, tolerability, pharmacokinetics and pharmacodynamic study of oral recombinant human interleukin-11 (oprelvekin)

Monette M. Cotreau, Lucille Stonis, Andrew Strahs, Ullrich S. Schwertschlag

Journal:

Biopharmaceutics & Drug Disposition

Year:

2004

Language:

english

File:

PDF, 70 KB

english, 2004

2

Randomized, controlled trial of recombinant human interleukin-11 in patients with active Crohn's disease

B. E. Sands, B. D. Winston, B. Salzberg, M. Safdi, C. Barish, L. Wruble, R. Wilkins, M. Shapiro, U. S. Schwertschlag, THE RHIL-11 CROHN'S STUDY GROUP

Journal:

Alimentary Pharmacology & Therapeutics

Year:

2002

Language:

english

File:

PDF, 232 KB

english, 2002

3

The influence of vinblastine and colchicine on renin secretion in vivo and in vitro

E. Hackenthal, U. Schwertschlag, R. Hackenthal

Journal:

Journal of Molecular Medicine

Year:

1978

Language:

english

File:

PDF, 736 KB

english, 1978

4

Beiträge zur Kenntnis der Bildung und Fauna der lithographischen Schiefer

J. Schwertschlager

Journal:

Paläontologische Zeitschrift

Year:

1926

Language:

german

File:

PDF, 1.37 MB

german, 1926

5

K16 expression in uninvolved psoriatic skin: a possible marker of pre-clinical psoriasis

Jag Bhawan, Cheryl Bansal, Kara Whren, Ullrich Schwertschlag, The IL-11 Psoriasis Study Group

Journal:

Journal of Cutaneous Pathology

Year:

2004

Language:

english

File:

PDF, 6.06 MB

english, 2004

6

TRIFLUOPERAZINE ANTAGONIZES INHIBITION OF RENIN RELEASE BY ANGIOTENSIN II

Ullrich Schwertschlag, Eberhard Hackenthal

Journal:

Clinical and Experimental Pharmacology and Physiology

Year:

1983

Language:

english

File:

PDF, 684 KB

english, 1983

7

Nonimmunological alterations of glomerular filtration by s-PAF in the rat kidney

Schwertschlag, Ullrich S, Dennis, Vincent W, Tucker, J Allan, Camussi, Giovanni

Journal:

Kidney International

Year:

1988

Language:

english

File:

PDF, 880 KB

english, 1988

8

Hematopoietic, immunomodulatory and epithelial effects of interleukin-11

Schwertschlag, US, Trepicchio, WL, Dykstra, KH, Keith, JC, Turner, KJ, Dorner, AJ

Journal:

Year:

1999

Language:

english

File:

PDF, 114 KB

english, 1999

9

Molecular classification of psoriasis disease-associated genes through pharmacogenomic expression profiling

Oestreicher, J L, Walters, I B, Kikuchi, T, Gilleaudeau, P, Surette, J, Schwertschlag, U, Dorner, A J, Krueger, J G, Trepicchio, W L

Journal:

The Pharmacogenomics Journal

Year:

2001

Language:

english

File:

PDF, 1.15 MB

english, 2001

10

Diagnosen neuer Rosenformen Bayerns

Prof. Dr. Jos. Schwertschlager

Journal:

Feddes Repertorium

Year:

1910

File:

PDF, 494 KB

1910

11

Histamine stimulates renin release from the isolated perfused rat kidney

Ullrich Schwertschlag, Eberhard Hackenthal

Journal:

Naunyn-Schmiedeberg's Archives of Pharmacology

Year:

1982

Language:

english

File:

PDF, 456 KB

english, 1982

12

MITIGATING EFFECTS OF INTERLEUKIN 11 ON CONSECUTIVE COURSES OF 5-FLUOROURACIL-INDUCED ULCERATIVE MUCOSITIS IN HAMSTERS

S.T. Sonis, A.G. Van Vugt, J. McDonald, E. Dotoli, U. Schwertschlag, P. Szklut, J. Keith

Journal:

Year:

1997

Language:

english

File:

PDF, 260 KB

english, 1997

13

Forskolin stimulates renin release from the isolated perfused rat kidney

Ullrich Schwertschlag, Eberhard Hackenthal

Journal:

European Journal of Pharmacology

Year:

1982

Language:

english

File:

PDF, 179 KB

english, 1982

14

The renin angiotensin aldosterone system and frusemide response in congestive heart failure.

S Reed, P Greene, T Ryan, B Cerimele, U Schwertschlag, M Weinberger, J Voelker

Journal:

British Journal of Clinical Pharmacology

Year:

1995

Language:

english

File:

PDF, 1.31 MB

english, 1995

15

A comparison of the effects of prostacyclin and 6-keto-prostaglandin E1 on renin release in the isolated rat and rabbit kidney

U. Schwertschlag, T. Stahl, E. Hackenthal

Journal:

Year:

1982

Language:

english

File:

PDF, 599 KB

english, 1982

16

No evidence of analgesic interference or CNS opioid withdrawal for TD-1211 in a phase 2b study in opioid-induced constipation (OIC)

Vickery, R., Webster, L., Li, Y., Schwertschlag, U., Singla, N., Canafax, D.

Journal:

The Journal of Pain

Year:

2013

Language:

english

File:

PDF, 91 KB

english, 2013

17

Mo1675 Pharmacokinetics and Tolerability of iOWH032, an Inhibitor of the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Chloride Channel, in Normal Volunteers and Cholera Patients

Schwertschlag, Ullrich, Kumar, Amresh, Kochhar, Sonali, Ings, Robert, Ji, Yuhua, de Hostos, Eugenio L., Choy, Robert, Salam, Mohammed, Khan, Wasif A., Lin, Patricia

Journal:

Gastroenterology

Year:

2014

Language:

english

File:

PDF, 59 KB

english, 2014

18

899 Td-1211 Phase 2B Study Demonstrates Increased Bowel Movement Frequency and Constipation-Related Symptom Improvement in Patients With Opioid Induced Constipation (OIC)

Vickery, Ross G., Li, Yu-Ping, Schwertschlag, Ullrich, Singla, Neil K., Webster, Lynn, Canafax, Daniel M.

Journal:

Gastroenterology

Year:

2013

Language:

english

File:

PDF, 61 KB

english, 2013

19

TD-1211 demonstrates a durable increase in bowel movement frequency and return toward normal bowel function in a 5-week Ph2b Opioid-Induced Constipation (OIC) study

Vickery, R., Li, Y., Schwertschlag, U., Singla, N., Webster, L., Canafax, D.

Journal:

The Journal of Pain

Year:

2013

Language:

english

File:

PDF, 91 KB

english, 2013

20

Painful clitoral tumescence during bromocriptine therapy

Blin, O., Schwertschlag, U.S., Serratrice, G.

Journal:

Year:

1991

Language:

english

File:

PDF, 346 KB

english, 1991

21

TD-1211 demonstrates tolerability and clinical activity following multiple treatment administration strategies in patients with opioid-induced constipation (OIC)

Singla, N., Canafax, D., Kang, A., Li, Y., Schwertschlag, U., Webster, L., Vickery, R.

Journal:

The Journal of Pain

Year:

2013

Language:

english

File:

PDF, 91 KB

english, 2013

22

A phase 1, randomized, double-blind, placebo-controlled dose-escalating, safety, tolerability, pharmacokinetic, and pharmacodynamic study of oral recombinant human interleukin eleven (O-rhIl-11) in normal healthy subjects

Cotreau, Monette M., Stonis, Lucille, Schwertschlag, Ullrich S.

Journal:

Gastroenterology

Year:

2003

Language:

english

File:

PDF, 170 KB

english, 2003

23

Randomized, Double Blind Controlled Trial of Subcutaneous Recombinant Human Interleukin-11 Versus Prednisolone in Active Crohn's Disease

Herrlinger, K.R., Witthoeft, T., Raedler, A., Bokemeyer, B., Krummenerl, T., Schulzke, J.D., Boerner, N., Kueppers, B., Emmrich, J., Mescheder, A., Schwertschlag, U., Shapiro, M., Stange, E.F.

Journal:

American Journal of Gastroenterology

Year:

2006

Language:

english

File:

PDF, 197 KB

english, 2006

24

Improved procedure for determination of flucytosine in human blood plasma by high-pressure liquid chromatography.

Schwertschlag, U, Nakata, L M, Gal, J

Journal:

Antimicrobial Agents and Chemotherapy

Year:

1984

Language:

english

File:

PDF, 583 KB

english, 1984

25

Suppression of endotoxin-inducible cytokines in whole blood from human subjects following single dose of recombinant human interleukin-11

Reznikov, L. L., Puren, A. J., Fantuzzi, G., Hamner, G. R., Schwertschlag, U. S., Ryan, J. L., Dinarello, C. A.

Journal:

Journal of Endotoxin Research

Year:

1999

Language:

english

File:

PDF, 83 KB

english, 1999

26

L-platelet activating factor induces changes on renal vascular resistance, vascular reactivity, and renin release in the isolated perfused rat kidney

Schwertschlag, U., Scherf, H., Gerber, J. G., Mathias, M., Nies, A. S.

Journal:

Circulation Research

Year:

1987

Language:

english

File:

PDF, 3.38 MB

english, 1987

27

Hemodynamic effects of platelet activating factor in the dog kidney in vivo

Scherf, H., Nies, A. S., Schwertschlag, U., Hughes, M., Gerber, J. G.

Journal:

Year:

1986

Language:

english

File:

PDF, 461 KB

english, 1986

28

Cellular Mechanisms of Renin Release

Hackenthal, E., Schwertschlag, U., Taugner, R.

Journal:

Clinical and Experimental Hypertension

Year:

1983

Language:

english

File:

PDF, 942 KB

english, 1983

29

The Antiparasitic Moxidectin: Safety, Tolerability, and Pharmacokinetics in Humans

Cotreau, Monette M., Warren, Sarah, Ryan, John L., Fleckenstein, Lawrence, Vanapalli, Sreenivasa R., Brown, Kenneth R., Rock, David, Chen, Chieh-Yu, Schwertschlag, Ullrich S.

Journal:

Journal of Clinical Pharmacology

Year:

2003

Language:

english

File:

PDF, 109 KB

english, 2003

30

Mechanism and Amelioration of Recombinant Human Interleukin-11 (rhIL-11)-Induced Anemia in Healthy Subjects

Dykstra, Kevin H., Rogge, Holly, Stone, Anne, Loewy, John, Keith, James C., Schwertschlag, Ullrich S.

Journal:

Journal of Clinical Pharmacology

Year:

2000

Language:

english

File:

PDF, 134 KB

english, 2000

31

SAFETY AND ACTIVITY EVALUATION OF rhlL-11 IN SUBJECTS WITH ACTIVE CROHNʼS DISEASE.

Bank, S, Sninsky, C, Robinson, M, Katz, S, Singleton, J, Miner, P, Safdi, M, Galandiuk, S, Hanauer, S, Varilek, G, Sands, B, Buchman, A, Rogers, V, Salzberg, B, Cai, B, Rogge, H, Schwertschlag, U

Journal:

Year:

1997

File:

PDF, 111 KB

1997

32

The Effects of Calcium and Calcium-Ionophores (X 537 a and a 23187) on Renin Release in the Isolated Perfused Rat Kidney

Schwertschlag, U., Hackenthal, E., Hackenthal, R., Rohs, G. H.

Journal:

Clinical Science

Year:

1978

Language:

english

File:

PDF, 286 KB

english, 1978

33

Intrarenal Conversion of Prostaglandin F 2α Into Prostaglandin E 2 and Renin Release in the Isolated Perfused Rat Kidney

Schwertschlag, U., Seyberth, H. W., Müller, H., Grunewald, R., Erlenmaier, T., Rohs, H. G., Hackenthal, E.

Journal:

Clinical Science

Year:

1980

Language:

english

File:

PDF, 243 KB

english, 1980

34

Multiple-Dose, Safety, Pharmacokinetics, and Pharmacodynamics of a New Selective Estrogen Receptor Modulator, ERA-923, in Healthy Postmenopausal Women

Cotreau, Monette M., Stonis, Lucille, Dykstra, Kevin H., Gandhi, Thimma, Gutierrez, Maria, Xu, Jing, Park, Young, Burghart, Peter H., Schwertschlag, Ullrich S.

Journal:

Journal of Clinical Pharmacology

Year:

2002

Language:

english

File:

PDF, 97 KB

english, 2002

35

Increased PGE2 excretion by dDAVP in humans depends on state of hydration

Schwertschlag, U., Gerber, J. G., Barnes, J. S., Nies, A. S.

Journal:

American journal of physiology. Renal physiology

Year:

1986

Language:

english

File:

PDF, 1.16 MB

english, 1986

36

Effect of Changes in Perfusion Pressure on Renal and Urinary Kallikrein in the Isolated Perfused Rat Kidney

B&ouml, nner, G., Schwertschlag, U., Marin-Grez, M., Gross, Franz

Journal:

Kidney & Blood Pressure Research

Year:

1983

Language:

english

File:

PDF, 970 KB

english, 1983

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